Effect of Tertiary Preventive Behavior on HbA1c Level, Quality of Life, and Complication Risk in Diabetes Mellitus Patients

Authors

  • Wardhatul Livia Master’s Program in Public Health, Universitas Sebelas Maret
  • Bhisma Murti Master’s Program in Public Health, Universitas Sebelas Maret
  • Didik Gunawan Tamtomo Faculty of Medicine, Universitas Sebelas Maret
  • Hanung Prasetya Study Program in Acupuncture, Health Polytechnics, Ministry of Health Surakarta

DOI:

https://doi.org/10.26911/jepublichealth.2024.09.01.10

Abstract

Background: Type 2 diabetes mellitus (DM) is a non-communicable disease which is a source of additional severity for other diseases. This study aims to determine the effect of tertiary preventive behavior on hba1c level, quality of life (QoL), and complication risk in diabetes mellitus patients.
Subjects and Method: This was a cross-sectional study conducted in Sukoharjo, Central Java, Indonesia, from October to November 2023. A total sample of 200 patients with type 2 diabetes mellitus (DM), registered in the Prolanis program, was selected through multistage random sampling. The independent variables were HbA1c levels, risk of complications, and QoL. The inde-pendent variable was tertiary preventive behavior. HbA1c levels were measured using spectrophotometer. QoL was measured using the WHOQOL questionnaire, and risk of complications using a questionnaire. Data were analyzed using the SEM model.
Results: Tertiary prevention behavior significantly increased HbA1c level (b= 0.31; CI 95%= -0.45 to 0.15; p<0.001) and quality of life (b= 0.15; 95% CI= -0.15 to 0.38; p<0.001). Tertiary prevention behavior significantly reduced the risk of complications (b= -0.22; CI 95%= -0.42 to 0.02; p= 0.026). The goodness-of-fit values suggest that the structural equation model (SEM) is acceptable (p= 0.188; RMSEA=0.04; CFI=0.97, TLI=0.95; SRMR=0.05; CD= 0.07).
Conclusion: Tertiary prevention behavior significantly increased HbA1c level and quality of life. Tertiary prevention behavior reduces the risk of complications in type 2 DM patients.

Keywords: Diabetes mellitus, HbA1c, complications, quality of life

References

Chaudhary N, Tyagi N (2018). Diabetes mellitus: An Overview. Int J Res Dev Pharm. 7(4): 3030–3033. doi: 10.21276/IJRDPL.2278.

DinkesProv Jateng (2021) dinkes prov 2021 Profil Kesehatan Jateng. Dinas Kesehatan Provinsi Jawa Tengah.

Dorans K, Bazzano L, Qi L, He H, Chen J, Appel L, Chen C et al. (2022). Effects of a Low-Carbohydrate Dietary Intervention on Hemoglobin A1c: A Randomized Clinical Trial. JAMA Network Open, 5(10): E2238645. doi: 10.1001/jamanetworkopen.2022.38645.

Fatony R, Tamtomo D, Prasetya H (2021). Effect of Curcuma Longa Rhizome Extract on Fasting Blood Sugar Levels and HbA1C in Type 2 Diabetes Mellitus : A Meta-Analysis. 06(2): 119–134. doi: 10.26911/theijmed.2021.06.02.01.

Galicia-Garcia U, Benito-Vicente A, Jebari S, Larrea-sebal A, Siddiqi H, Uribe K, Ostolazia H et al. (2020). Pathophysiology of type 2 diabetes mellitus. Int J Mol Sci. 21(17): 1–34. doi: 10.3390/ijms21176275.

Ghavami H, Radvar M, Moloud R, Soraya S, Shams (2018). Effect of lifestyle interventions on diabetic peripheral neuropathy in patients with type 2 diabetes, result of a randomized clinical trial. Agri J Turkish Soc Algology. 30: 165–170. doi: 10.5505/agri.2018.45477.

Hwang C, Lim, Yoo J, Kim H, Hwang M, Handberg E, Petersen J, et al. (2019). Effect of all-extremity high-intensity interval training vs. moderate-intensity continuous training on aerobic fitness in middle-aged and older adults with type 2 diabetes: A randomized controlled trial. Elsevier: Experimental Gerontology, 116: 46–53. doi: 10.1016/J.EXGER.2018.12.013.

IDF (2021) IDF Diabetes Atlas 10th edition. International Diabetes Federation

IDF (2023) Type 2 diabetes. International Diabetes Federation

Islami D, Tamtomo D, Prasetya H (2021). Correlation between Family Support and Self Care in Type 2 Diabetes Mellitus : Meta-Analysis. Med J Indones. 06(01): 62–70. doi: 10.26911/theijmed.2021.06.01.07.

Kemenkes RI (2020). Kemkes 2020 info-datin Diabetes Melitus. Kementrian Kesehatan Republik Indonesia

Kisling L, Joe, Das M (2023) Prevention Strategies. NCBI NIH Goverment.

Kurniawati O, Prasetya H, Murti B (2020). Meta-Analysis the Effects of Obesity and Type 2 Diabetes Mellitus on COVID-19 Mortality. J Epidemiol Public Health. 06: 177–191. doi: 10.26911/jepublichealth.2021.06.02.05.

Kusumaningrum U, Murti B, Prasetya H. (2022). Meta-Analysis of the Effects of Diet and Physical Activity on HbA1c in Type II Diabetes Mellitus Patients. Medical J Indones, 7(2): 172–187. doi: 10.26911/theijmed.2022.07.02.06.

Nathan D, Lachin J, Bepu I, Burch H, Buse J, Cherington A, Fortman S (2022). Glycemia Reduction in Type 2 Diabetes-Microvascular and Cardiovascular Outcomes. Engl J Med. 1075–1088. doi: 10.1056/NEJMoa2200436.

Russo C, Walicha M, Caponnetto P, Cibella F, Maglia M, Alamo A, Campagna D, et al. (2022). Efficacy and Safety of Varenicline for Smoking Cessation in Patients With Type 2 Diabetes A Randomized Clinical Trial. 5(6): 1–14. doi: 10.1001/jamanetworkopen.2022.17709.

Septiani A, Rahardjo S, Prasetya H (2020). Meta-Analysis of Risk Factors for Lower Extremity Amputation in Diabetes Mellitus Patients with Foot Ulcers. Medical J Indones. 05(04): 343-355. doi: 10.26911/theijmed.2020.05.04.10.

Sholihah A, Tamtomo D, Prasetya H (2021). Meta-Analysis of the Effect of Telemonitoring on Blood Sugar Levels and Quality of Life in Diabetes Patients’, 06(03): 246–257. doi: 10.26911/theijmed.2021.06.03.02.

Ueki K, Sasako T, Okazaki Y, Miyake K, Nangaku M, Ohashi Y, Noda M, et al. (2021). The multifactorial intervention has a significant effect on diabetic kidney disease in patients with type 2 diabetes. Kidney Int. 99(1): 256–266. doi: 10.1016/j.kint.2020.08.012.

Umphonsathien M, Rattanasian P, Lokatta-chariya S, Suansawa W, Boonyasuppa-yakom K, Khovidhunkit W (2022) .Effects of intermittent very-low-calorie diet on glycemic control and cardiovascular risk factors in obese patients with type 2 diabetes mellitus: A randomized controlled trial. J Diabet Investig. 13(1): 156–166.

Vos T (2020). Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet, 396 (10258): 1204–1222. doi: 10.1016/S0-140-6736(20)30925-9.

Downloads

Published
2024-01-16

Issue
Vol. 9 No. 1 (2024)

Section
flow-chart-line Articles

How to Cite
Livia, W., Murti, B., Tamtomo, D. G., & Prasetya, H. (2024). Effect of Tertiary Preventive Behavior on HbA1c Level, Quality of Life, and Complication Risk in Diabetes Mellitus Patients. Journal of Epidemiology and Public Health, 9(1), 106–116. https://doi.org/10.26911/jepublichealth.2024.09.01.10

Most read articles by the same author(s)

<< < 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 > >>