Meta-Analysis the Effect of Malaria Infection on Anemia in Pregnant Women

Authors

  • Firdausi Nuzula Masters Program in Public, Universitas Sebelas Maret
  • Setyo Sri Rahardjo Faculty of Medicine, Universitas Sebelas Maret
  • Bhisma Murti Masters Program in Public, Universitas Sebelas Maret

Abstract

Background: Malaria is an important threat to pregnant women, with an increased risk for both mother and newborn, especially in the first and second pregnancies caused by P. falciparum. Malaria infection in pregnant women can cause anemia in the mother and fetus, as well as babies with low birth weight, this can increase maternal and infant mortality rates. This study aims to analyze the magnitude of the influence of malaria infection in pregnant women on the incidence of anemia based on a number of previous similar studies.

Subjects and Method: This was a systematic review and meta-analysis carried out by following the PRISMA flow diagram. The process of searching for articles is carried out through a journal database which includes: Google Scholar, PubMed, and Science Direct by selecting articles published in 2010-2020. Key words used include: "malaria infection" AND "pregnancy women" OR "anemia" AND "adjusted odds ratio". The inclusion criteria were full paper articles with observational study design, articles in English, multivariate analysis used with adjusted odds ratios. Articles that meet the requirements are analyzed using the Revmen 5.3 application.

Results: A total of seven articles were reviewed in this study with a cross-sectional study design. A meta-analysis of 7 cross-sectional studies showed that malaria infection had a 1.72 times increased risk of anemia in pregnant women compared to those not infected with malaria (aOR 1.72; 95% CI 1.43 to 2.07; p <0.001).

Conclusion: Malaria infection increases the risk of anemia in pregnant women.

Keywords: malaria infection, pregnancy, anemia, meta-analysis

Correspondence: Firdausi Nuzula. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: ulafn10@gmail.com.

Journal of Epidemiology and Public Health (2020), 05(04): 489-498

https://doi.org/10.26911/jepublichealth.2020.05.04.11

References

Alvarez MV, Ou

in pregnancy with sulphadoxinepyri-methamine in Benin. Trop Med Int Healt. 23 (6): 582

Anulus A, Murti B, Prasetya H (2019). Risk factors of HIV among male military personnels: A Meta Analysis. J Health Promot and Behav. 4(3): 178

Bauserman M, Conroy AL, North K, Patterson J, Bose C, Meshnick S (20). An overview of malaria in pregnancy. Semin Perinatol. 43(5): 282

Budiyanto A, Wuriastuti T (2017). Faktor yang berhubungan dengan kejadian malaria pada ibu hamil di Indonesia (Factors associated with the incidence of Malaria in Pregnant Women in Indonesia). Media Penelitian dan Pengembangan Kesehatan. 27(1): 25

CDC (2020). Parasites - Malaria. Retrieved from https://www.cdc.gov/parasite-s/malaria/index.html.

CEBMa (2014). Critical Appraisal. Amster-dam: Center for Evidence Based Management.

Chaponda EB, Chandramohan D, Michelo C, Mharakurwa S, Chipeta J, Chico RM (2015). High burden of malaria infection in pregnant women in a rural district of Zambia: A cross-sectional study. Malaria Journal. 14(1): 1

Cisse M, Sangare I, Lougue G, Bamba S, Bayane D, Guiguemde RT (2014). Prevalence and risk factors for Plasmodium falciparum malaria in pregnant women attending antenatal clinic in Bobo-Dioulasso (Burkina Faso). BMC Infectious Diseases. 14(1): 1

Corr

Feleke BE (2016). Maternal HIV status affects the infant hemoglobin level: A comparative cross-sectional study. Medicine (United States).9(3): 1

Fondjo LA, Addai-Mensah O, Annani-Akollor ME, Quarshie JT, Boateng AA, Assafuah SE, Owiredu EW (2020). A multicenter study of the prevalence and risk factors of malaria and anemia among pregnant women at first antenatal care visit in Ghana. PLoS ONE.15(8): e0238077. https://doi.org/10.1371/journal.pone.0238-077.

Kementerian Kesehatan RI (2014). Profil Kesehatan Indonesia Tahun 201. Jakarta: Kementerian Kesehatan RI. https://doi.org/10.101/CBO9781107415324.004.

Kementerian Kesehatan RI (2019). Profil Kesehatan Indonesia 2019. Kemente-rian Kesehatan RI. 8 (9): 1

Mlugu EM, Minzi O, Kamuhabwa AAR, Aklillu E (2020). Prevalence and correlates of asymptomatic malaria and anemia on first antenatal care visit among pregnant women in Southeast, Tanzania. International Journal of Environmental Research and Public Health. 17(9). https://doi.org/10.3390/ijerph17093123.

Murti B (2018). Prinsip dan metode riset epidemiologi (The Principles and Research Methods of Epidemiology). 5th edn. Surakarta: Universitas Sebelas Maret.

Olukosi AY, Olakiigbe A, Ajibaye O, Orok BA, Aina OO, Akindele SK, Akinyele OO et al. (2020). Socio-economic behavioural indicators of falciparum malaria parasitaemia and moderate to severe anaemia among pregnant women attending antenatal clinics in Lagos, Southwest Nigeria. Malaria Journal. 19(1): 1

Rogerson SJ, Desai M, Mayor A, Sicuri E, Taylor SM, van Eijk AM (2018). Burden, pathology, and costs of malaria in pregnancy: new developments for an old problem. Lancet Infect Dis. 18(4): e107-e118. https://doi.org/10.1016/S14733099(18)30066-5.

V

Wabula WM, Suryadhi NT, Ani LS (2014). Hubungan antara konsumsi tablet besi dan infeksi malaria dengan ane-mia pada ibu hamil di Kota Ambon (Relationship between iron tablet consumption and malaria infection with anemia in pregnant women in Ambon City). Public health prev. med. arch. 2(2): 131. https://doi.org/10.15562/phpma.v2i2.139.

WHO (2019). World malaria report 2019. Retrieved from: https://www.who.int/newsroom/fact-sheets/detail/-malaria.

Downloads

Published
2020-10-16

Issue
Vol. 5 No. 4 (2020)

Section
flow-chart-line Articles

How to Cite
Nuzula, F., Rahardjo, S. S., & Murti, B. (2020). Meta-Analysis the Effect of Malaria Infection on Anemia in Pregnant Women. Journal of Epidemiology and Public Health, 5(4), 489–498. Retrieved from https://jepublichealth.com/index.php/jepublichealth/article/view/360

Most read articles by the same author(s)

<< < 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 > >>