Meta-Analysis: Effects of Smoking, Alcohol Consumption, and Low Physical Activity on Osteoporosis in Adults
DOI:
https://doi.org/10.26911/jepublichealth.2024.09.01.03Abstract
Background: Osteoporosis is a systemic skeletal disease characterized by low mineral bone mass and microarchitectural deterioration of bone tissue. This study aims to analyze the effect of smoking, alcohol consumption, and low physical activity on osteoporosis in adults.
Subjects and Method: This was a meta-analysis study using the PICO format. Population: Adults, Intervention: Smoking, Alcohol Consumption, Low Physical Activity, Comparison: No Smoking, No Alcohol Consumption, High Physical Activity, Outcome: Osteoporosis. Articles were searched using online databases such as PubMed, Google Scholar, Science Direct. The search for articles using the keywords "Smoking" OR "Tobacco" AND "Alcohol consumption" OR "Drinking" AND "Physical activity" OR "Exercise" AND "Osteoporosis" OR "Bone mineral density" AND "Cross-sectional". The inclusion criteria for articles used were articles published in 2013-2023. Articles were filtered using PRISMA flow diagrams and analysis was conducted using RevMan 5.4.
Results: The meta-analysis used 15 articles with cross-sectional studies from Ireland, Nepal, Taiwan, South Korea, China, Iran, America, Brazil, India, Congo, and Thailand with a total sample of 111,478 samples. The risk of osteoporosis increased with smoking (aOR= 1.49; CI 95%= 1.04 to 2.16; p= 0.030), alcohol consumption (aOR= 1.04; CI 95%= 0.84 to 1.30; p = 0.690), and low physical activity (aOR= 1.17; CI 95%= 0.92 to 1.48; p= 0.210).
Conclusion: Smoking, alcohol consumption, and low physical activity increase the risk of osteoporosis in adults.
Keywords: smoking, alcohol consumption, physical inactivity, osteoporosis.
References
Abdolalipour S, Mirghafourvand M, Ghassab-Abdollahi N, Farshbaf-Khalili A (2021). Health-promoting lifestyle and quality of life in affected and unaffected menopausal women by primary osteoporosis. J Educ Health Promot. 10(1): 45. doi: 10.41-03/jehp.jehp_450_20.
Ahmed W, Muhammad T, Muneera K (2023). Prevalence of early and late onset of chronic diseases and multi-morbidity and its association with physical, mental and functional health among older Indian adults. BMC Geriatrics. 23(1): 1–15. doi: 10.1186/s-12877-023-04264-8
Aibar-Almazán A, Voltes-Martínez A, Castellote-Caballero Y, Afanador-Restrepo DF, Carcelén-Fraile M del C, López-Ruiz E (2022). Current status of the diagnosis and management of oteoporosis. Int J Mol Sci. 23(16): 1–27. doi: 10.3390/ijms23169465.
Anam AK, Insogna K (2021). Update on osteoporosis.screening.and.management. Med Clin North Am, 105(6):1117–1134. doi:10.1016/j.mcna.2021.05.016
Burke ÉA, Carroll R, Ding AW, Yaman M, Walsh JB, McCallion P, McCarron M (2021). Men’s Bones Matter Too, a Cross Sectional Study Examining Bone Health among Men with Intellectual Disability in Ireland. OBM Geriatrics. 05(04):.1–22. doi: 10.21926/obm.geriatr.2104182.
Chaudhary NK, Timilsena MN, Sunuwar DR, Pradhan PMS, Sangroula RK (2019). Association of Lifestyle and Food Consumption with Bone Mineral Density among People Aged 50 Years and Above Attending the Hospitals of Kathmandu, Nepal. J Osteoporos. 2019: 1–6. doi:10.1155/2019/1536394.
Choi KH, Park SM, Park JS, Park JH, Kim KH, Kim MJ (2013). Prevalence of and Factors Associated with Osteoporosis among Korean Cancer Survivors: A Cross-Sectional Analysis of the Fourth and Fifth Korea National Health and Nutrition Examination Surveys. Asian Pac j Cancer Prev. 14(8): 4743–4750. doi: 10.7314/APJCP.2013.14.8.4743.
Eckstrom E, Neukam S, Kalin L, Wright J (2020). Physical activity and healthy aging. Clin Geriatr Med. 36(4): 671–683. doi: 10.1016/j.cger.2020.06.009.
Félix-Beltrán L, Seixas BV (2021). Childhood hunger experiences and chronic health conditions later in life among Brazilian older adults. Rev Panam Salud Publica. 45:.1–10. doi: 10.26633/RPSP.2021.39.
Huang JF, Tan QC, Bai H, Wang J, Bergman M, Wu Z (2022). Bone mineral density, osteopenia and osteoporosis among US adults with cancer. QJM-Int J Med. 115(10):.653–660. doi: 10.1093/qjmed/hcac015.
IOF (2023). Diagnosis of Osteoporosis. International Osteoporosis Foundation.
Johnston CB, Dagar M (2020). Osteoporosis in older adults. Med Clin North Am. 104(5):.873–884. doi: 10.1016/j.mcna.2020.06.004.
LeBoff MS, Greenspan SL, Insogna KL, Lewiecki EM, Saag KG, Singer AJ, Siris ES (2022). The clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int. 33(10): 2049–2102. doi: 10.1007/s00198-021-05900-y.
Lee S, Ko K, Shin S, Park HS, Hong N, Rhee Y (2023). Adipopenia is associated with osteoporosis in community-dwelling non-underweight adults independent of sarcopenia. Arch Osteo-poros. 18(1): 44. doi: 10.1007/s11657-023-01233-x.
Mavinga A, Mbuyi J, Matanda D, Lebughe P, Mulumba JC, Nyembue V, Lukusa A, et al. (2022). Prevalence and determinants of osteoporosis in Congolese patients with axial rheumatism: a cross-sectional hospital-based study. Pan Afr Med J. 43:1–11. doi: 10.11604/pamj.2022.43.100.31519.
Min C, Yoo DM, Wee JH, Lee HJ, Choi HG (2021). High-Intensity Physical Activity with High Serum Vitamin D Levels is Associated with a Low Prevalence of Osteopenia and Osteoporosis: A Population-Based Study. Osteoporos Int..32(5):.883–891. doi: 10.1007/s00198-020-05746-w.
Murti B (2023) Penilaian kritis (critical appraisal) studi cross-sectional analitik (bukan survey) untuk penelitian meta-analisis. Universitas Sebelas Maret.
Rondanelli M, Faliva MA, Barrile GC, Cavioni A, Mansueto F, Mazzola G, Oberto L, et al. (2021). Nutrition, physical activity, and dietary supplementation to prevent bone mineral density loss: A food pyramid. Nutrients. 14(1); 1–60. doi: 10.3390/nu14010074.
Tański W, Kosiorowska J, Szymańska-Chabowska A (2021). Osteoporosis – risk factors, pharmaceutical and non-pharmaceutical treatment. Eur Rev Med Pharmacol Sci. 25(9): 3557–3566. doi: 10.26355/eurrev_202105_25838.
Wongsuttilert A, Chanchai S, Jaidee W (2015). Risk Factors Affecting Bone Health in Middle-aged Group. Burapha Univ. Int Conf.
Yang CY, Lai JCY, Huang WL, Hsu CL, Chen SJ (2021). Effects of sex, tobacco smoking, and alcohol consumption osteoporosis development: Evidence from Taiwan biobank participants. Tob Induc Dis. 19(6): 1–8. doi: 10.18332/tid/136419.
Younesi AL, Kashanian M, Najmi Z, Mahdavi A, SafarpourLima Z (2023). Risk factors of osteoporosis and osteopenia in postmenopausal women based on the L2–L4 BMD T score of the lumbar spine: a study in Iran. Gynecol Endocrinol. 39(1): 1–7. doi: 10.1080/09513590.2023.2205959.
Zhang X, Dai Z, Lau EHY, Cui C, Lin H, Qi J, Ni W, et al. (2020). Prevalence of bone mineral density loss and potential risk factors for osteopenia and osteoporosis in rheumatic patients in China: logistic regression and random forest analysis. Ann Transl Med. 8(5): 226. doi: 10.21037/atm.2020.01.08.
Zheng M, Wan Y, Liu G, Gao Y, Pan X, You W, Yuan D, et al. (2023). Differences in the prevalence and risk factors of osteoporosis in chinese urban and rural regions: a cross-sectional study. BMC Musculoskelet Disord. 24(1): 46. doi: 10.1186/s12891-023-06147-w.
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Published
2024-02-22
Issue
Vol. 9 No. 1 (2024)
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