COVID-19 Patient Mortality with Convalescent Plasma Therapy: Meta-Analysis

Authors

  • Fathiyyatu Assa’diy Firda Masters Program in Public Health, Universitas Sebelas Maret
  • Bhisma Murti Masters Program in Public Health, Universitas Sebelas Maret
  • Cri Sajjana Prajna Wekadigunawan Universitas Esa Unggul, Jakarta, Indonesia

Abstract

Background: The use of convalescent plasma was recommended as empiric treatment during the Ebolavirus outbreak in 2014, and a protocol for the treatment of Middle East Respiratory Syndrome coronavirus (MERS) with convalescent plasma was created in 2015. These findings raise the hypothesis that the use of convalescent plasma transfusion may be beneficial in SARS-infected patients. -CoV-2. The aim of this study was to estimate the mortality risk of COVID-19 patients with convalescent plasma therapy.

Subjects and method: A systematic review and meta-analysis was carried out by collecting articles from the Google Scholar, PubMed, and Science Direct databases. The articles were screened using the PICO model, including: (1) Population= confirmed COVID-19 patients, (2) Intervention= conva

References

Abraham J (2019). Passive antibody therapy in COVID-19. Nature Reviews Immunology. 5(3): 4-6. DOI:10.1038/s-41577-020-0365-7.

Agarwal A, Mukherjee A, Kumar G, Chatterjee P, Bhatnagar T, Malhotra P (2020). Convalescent plasma in the management of moderate covid-19 in adults in India: open label phase II multicentre randomised controlled trial. BMJ. 371(3939):1-10. DOI:10.1136/BMJ.M3939.

AlQahtani M, Abdulrahman A, Almadani A, Alali SY, Al Zamrooni AM, Hejab AH, Conroy RM et al. (2021). Randomized controlled trial of convalescent plasma therapy against standard therapy in patients with severe COVID-19 disease. Scientific Reports, 11(1): 1

Balcells ME, Rojas L, Le Corre N, Mart

Choi JY (2020). Convalescent plasma therapy for coronavirus disease 2019. In Infection and Chemotherapy. 52(3): 307

Gharbharan A, Jordans CCE, Geurtsvan-kessel C, Hollander JG Den, Karim F, Mollema FPN et al. (2020). Convalescent Plasma for COVID-19 . A randomized clinical trial. MedRxiv. 14(3):1

Joyner MJ, Carter RE, Senefeld JW, Klassen SA, Mills JR, Johnson PW, Theel ES et al. (2021). Convalescent plasma antibody levels and the risk of death from Covid-19. New England J Med. 384 (11): 1015

Li Y, Xia L (2020). Coronavirus Disease 2019 (COVID-19): Role of Chest CT in Diagnosis and Management. American Journal of Roentgenology, 214(32): 1280

Li ZW, Hu Y, Tong X, Zheng (2020). Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19: A Randomized Clinical Trial. JAMA. 324(5): 460

Libster R, P

Mikolajewicz N, Komarova SV (2019). Meta-analytic methodology for basic research: A practical guide. Frontiers in Physiology. 10(5). DOI:10.3389/fphys.2019.00203

Murti B (2018). Prinsip dan Metode Riset Epidemiologi (Epidemiological Research Principles and Methods) (5th ed.). Program Studi Ilmu Kesehatan Masyarakat, Program Pascasarjana, Universitas Sebelas Maret.

O

Rasheed AM, Fatak DF, Hashim HA, Mau-lood MF, Kabah KK, Almusawi YA, Abdulamir AS (2020). The therapeutic potential of convalescent plasma therapy on treating critically-ill covid-19 patients residing in respiratory care units in hospitals in baghdad, Iraq. Infezioni in Medicina, 28(3): 357

Salazar E, Christensen PA, Graviss EA, Nguyen DT, Castillo B, Chen J, Lopez B et al. (2020). Treatment of Coronavirus Disease 2019 Patients with Con-valescent Plasma Reveals a Signal of Significantly Decreased Mortality. Am J Pathology. 190(11): 2290

Salazar M, Gonz

Simonovich VA, Burgos Pratx LD, Scibona P, Beruto MV, Vallone MG, V

Downloads

Published
2021-12-07

Issue
Vol. 6 No. 3 (2021)

Section
flow-chart-line Articles

How to Cite
Firda, F. A., Murti, B., & Wekadigunawan, C. S. P. (2021). COVID-19 Patient Mortality with Convalescent Plasma Therapy: Meta-Analysis. Journal of Epidemiology and Public Health, 6(3), 281–290. Retrieved from https://jepublichealth.com/index.php/jepublichealth/article/view/421

Most read articles by the same author(s)

<< < 1 2 3 4 5 6 7 8 9 10 11 12 13 14 > >>