Environmental Factors Associated with Pneumonia in Children Under-Five in Nduga District, Papua

Authors

  • Yulianda Yeimo Masters Program in Public Health, Universitas Sebelas Maret
  • Isna Qadrijati Faculty of Medicine, Universitas Sebelas Maret
  • Bhisma Murti Masters Program in Public Health, Universitas Sebelas Maret

Abstract

Background: Pneumonia is an inflammatory condition of the lung affecting primarily the small air sacs known as alveoli. In 2016 UNICEF had reported that pneumonia remains the leading infectious cause of death among children under five, killing approximately 2,400 children a day. Mortality due to childhood pneumonia is strongly associated to poverty, lack of safe water and sanitation, indoor air pollution and absence of basic immunization. This study aimed to determine the environmental factors associated with pneumonia in children under-five in Nduga, Papua, Indonesia.

Subjects and Method: This was an analytic observational study with case-control design. This study was conducted in Yigi and Mbua Sub-districts, Nduga District, Papua, Indonesia, from December 2017 to February 2018. A sample of 184 children under-five consisting of 88 children with pneumonia (case) and 96 children without pneumonia (control), was selected for this study by fixed disease sampling. The independent variables were BCG immunization status, family income, indoor household air pollution, and environmental sanitation. The dependent variable was pneumonia. Data were collected by questionnaire and medical record. The data were analyzed by a multiple logistic regression.

Results: The risk of pneumonia in children under-five increased by absence of BCG immunization (OR= 6.15; 95% CI= 2.78 to 13.61; p< 0.001), poor indoor household air pollution (OR= 5.68; 95% CI= 2.63 to 12.26; p< 0.001), and poor sanitation (OR= 5.06; 95% CI= 2.16 to 11.83; p<0.001). The risk of pneumonia in children under-five decreased by higher family income (OR= 0.30; 95% CI= 0.13 to 0.70; p= 0.005).

Conclusion: Pneumonia in children under five is associated with indoor household air pollution, poor sanitation, absence BCG immunization, and lower family income.

Keywords: pneumonia, indoor pollution, sanitation, BCG immunization, family income

Correspondence:

References

Barregard L, Sallsten G, Almstrand AC, Gustafson P, Andersson M, Olin A (2008). Experimental exposure to wood smoke: effects on airway inflammation and oxidative stress, Occup Environ Med. 65(5): 319

Brown J, Cairncross S, and Ensink J HJ. (2013). Water, sanitation, hygiene and enteric infections in children. Archives of Disease in Childhood. 98(8): 629

Diette GB, Accinelli RA, Balmes JR, Buist AS, Checkley W, Garbe P, Hansel NN, et al. (2012). Obstructive lung disease and exposure to burning biomass fuel in the indoor environment. Global Heart. pp. 265

Faustman DL, Wang L, Okubo Y, Burger D, Ban L, Man G, Zheng H, et al. (2012). The proof of concept, randomized, the controlled clinical trial of Bacillus Calmette Guerin for treatment of long-term type 1 diabetes. PLoS ONE, 7(8).

Fullerton DG, Bruce N, and Gordon SB. (2008). Indoor air pollution from biomass fuel smoke is a major health concern in the developing world. Transactions of the Royal Society of Tropical Medicine and Hygiene. pp. 843

Gordon SB, Irving GRB, Lawson RA, Lee ME, Read RC. (2000) Intracellular trafficking and killing of Streptococcus pneumoniae by human alveolar macrophages are influenced by opsonins, Infection and Immunity. 68(4): pp. 2286

Gordon SB, Bruce NG, Grigg J, Hibber PL, Kurmi OP, Lam K, Hubert, Mortimer, Kevin. (2014) Respiratory risks from household air pollution in low and middle-income countries. The Lancet Respiratory Medicine. pp. 823

Heinzerling AP, Guarnieri, Michael J, Mann JK, Diaz JV, Thompson LM. Diaz A, Bruce NG. et al. (2016). Lung function in wood smoke exposed Guatemalan children following a chimney stove intervention. Thorax, 71(5): 421

Kementerian Kesehatan Republik Indo-nesia. (2012). Profil Data Kesehatan Indonesia Tahun 2011. Jakarta: Kementerian Kesehatan RI.

Kleinnijenhuis J, Quintin J, Preijers F, Benn CS, Joosten LAB, Jacobs C, Loenhout JV. et al. (2015). Long-lasting effects of BCG vaccination on both heterologous Th1/Th17 responses and innate trained immunity. NIH Public Access. 6(2): pp. 152

Kliegman RM. (2016). Nelson TEXTBOOK of PEDIATRICS, Edition 17.

Leonard SS, Wang S, Shi X, Jordan BS, Castranova V, Dubick MA. (2000). Wood smoke particles generate free radicals and cause lipid peroxidation, DNA damage, NF?B activation and TNF-? release in macrophages. Toxicology. 150(1

Leung DT, Chisti MJ, and Pavia A T. (2016). Prevention and Control of Childhood Pneumonia and Diarrhea. Pediatric Clinics of North America: 67

Rylance J, Fullerton DG, Scriven J, Aljurayyan AN, Mzinza D, Barrett S, Wright, Adam KA. et al. (2015). Household air pollution causes dose-dependent inflammation and altered phagocytosis in human macrophages. American Journal of Respiratory Cell and Molecular Biology. 52(5): 584

Semple S, Devakumar D, Fullerton DG, Thorne PS, Metwali N, Costello A, Gordon SB, et al. (2010). Airborne endotoxin concentrations in homes burning biomass fuel. Environmental Health Perspectives. 118(7): 988

Smith KR, McCracken JP, Weber MW, Hubbard A, Jenny A, Thompson LM, Balmes J, et al. (2011). Effect of reduction in household air pollution on childhood pneumonia in Guatemala (RESPIRE): A randomized controlled trial. The Lancet. 378 (9804): 1717

Triccas JA, Counoupas C (2016). Novel vaccination approaches to prevent tuberculosis in children. Pneumonia. 8(1): 18.

World Health Organization and The United Nations Children

Xu F, Droemann D, Rupp J, Shen H, Wu X, Goldmann T, Hippenstiel S. et al. (2008). Modulation of the inflammatory response to Streptococcus pneumoniae in a model of acute lung tissue infection. Am J Respir Cell Mol Biol. 39(5): 522

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Published

2018-06-26

How to Cite

Yeimo, Y., Qadrijati, I., & Murti, B. (2018). Environmental Factors Associated with Pneumonia in Children Under-Five in Nduga District, Papua. Journal of Epidemiology and Public Health, 3(3), 307–311. Retrieved from https://jepublichealth.com/index.php/jepublichealth/article/view/85

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