Effects of Overweight and Obesity on Hypertension in Adolescents: A Meta-Analysis

Authors

  • Nurussyifa Afiana Zaen Masters Program in Public Health, Universitas Sebelas Maret http://orcid.org/0000-0002-2632-3671
  • Didik Tamtomo Faculty of Medicine, Universitas Sebelas Maret
  • Burhannudin Ichsan Faculty of Medicine, Universitas Muhammadiyah Surakarta

DOI:

https://doi.org/10.26911/jepublichealth.2023.08.01.10

Abstract

Background: Hypertension is currently starting to show a trend in prevalence that continues to increase at a younger age and is a major cause of premature death in the world. In adolescents, hypertension is more common who are overweight or obese. This study aims to examine the effect of overweight and obesity on the incidence of hypertension in adolescents using a meta-analysis.
Subjects and Method: Meta-analysis was carried out using the PRISMA flow chart and the PICO model. Population: adolescents aged 10 to 19 years. Intervention: overweight and obesity. Comparison: normoweight. Outcome: hypertension). The databases used are PubMed, Science Direct, Springer Link, and Google Scholar with the keywords (hypertension OR "High Blood Pressure") AND "BMI Status" AND (adolescent OR teenager) AND "cross sectional". There were 9 cross-sectional studies published in 2012-2022 with odds ratio (OR) effect size that met the inclusion criteria. Analysis was performed with RevMan 5.3.
Results: A meta-analysis was conducted on 9 articles with a cross-sectional study design originating from China, South Korea, India, Turkey, Tunisia, Lithuania and Poland involving 63,239 adolescents aged 10-19 years. The results of the meta-analysis showed that overweight adolescents were 2.44 times more likely to experience hypertension compared to normal weight adolescents (aOR= 2.44; 95%CI= 1.87 to 3.19; p<0.001), and obese adolescents were more likely to experience hypertension 4.53 times compared with normal weight adolescents (aOR= 4.53; 95% CI= 3.10 to 6.61; p<0.001).
Conclusion: Being overweight and obese can increase the risk of developing hypertension in adolescents.

Keywords: overweight, obesity, hypertension, adolescents, meta-analysis

Correspondence:
Nurussyifa Afiana Zaen. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: nurussyifaaz20@gmail.com. Mobile: +6287723131415.

References

Aounallah-Skhiri H, Ati JE, Traissac P, Romdhane HB, Eymard-Duvernay S, Delpeuch F, Achour N, et al. (2012). Blood pressure and associated factors in a North African adolescent population. a national cross-sectional study in Tunisia. BMC Pub Health. 12(98). doi: 10.1186/1471-2458-12-98.

Brady TM (2017). Obesity-related hypertension in children. Front Pediatr. 5(197): 1–7. doi: 10.3389/fped.2017.00197.

Çam HH, Top FU (2020). Prevalence of hypertension and its association with body mass index and waist circumference among adolescents in Turkey: A cross-sectional study. J Pediatr Nurs. 57: e29–e33. doi: 10.1016/j.pedn.2020.09.017.

CDC (2020). High blood pressure in kids and teens. Centers for Disease Control and Prevention. Retrieved September 10, 2022, from https://www.cdc.gov/bloodpressure/youth.htm.

CDC (2021). Defining childhood weight status. Centers for Disease Control and Prevention. Retrieved September 13, 2022, from https://www.cdc.gov/obesity/basics/childhood-defining.html.

CDC (2022). Facts about hypertension. Centers for Disease Control and Prevention. Retrieved September 10, 2022, from https://www.cdc.gov/bloodpressure/facts.htm.

Dulskiene V, Kuciene R, Medzioniene J, Benetis R (2014). Association between obesity and high blood pressure among Lithuanian adolescents: A cross-sectional study. Ital J Pediatr. 40(102). doi: 10.1186/s13052-014-0102-6.

Febriani RT, Sari NL (2020). Hypertension risk factors among obese adolescent. In The 7th International Conference on Public Health. doi: 10.26911/the7thicph.01.02.

Flynn JT (2019). The hypertensive adolescent. CJASN. 14(7): 1074–1076. doi: 10.2215/CJN.02800319.

Huang Y, Zheng H, Qin S, Chen C, Su D, Ye B, Huang Y, et al. (2022). Prevalence and risk factors of hypertension in adolescents: A cross-sectional study based on junior high schools in southwest China. Res Sq. doi: 10.21203/rs.3.rs2194101/v1.

JBI (2017). Checklist for analytical cross-sectional studies. Joanna Briggs Institute Retrived October 29, 2022, from https://jbi.global/sites/default/files/201905/JBI_Critical_AppraisalChecklist_for_Analytical_Cross_Sectional_Studies2017_0.pdf.

Kaczmarek M, Stawińska-Witoszyńska B, Krzyżaniak A, Krzywińska-Wiewiorows-ka M, Siwińska A (2015). Who is at higher risk of hypertension? Socio-economic status differences in blood pressure among Polish adolescents: a population-based ADOPOLNOR study. Eur J Pediatr. 174: 1461–1473. doi: 10.1007/s00431-015-2554-0.

Karimulla S, Rao NP (2021). Prevalence of obesity and hypertension in adolescent school children of Guntur town, Andhra Pradesh. Int J Contemp Med Res. 8(7): G1–G4. doi: 10.21276/ijcmr.2021.8.7.1.

Kelly RK, Magnussen CG, Sabin MA, Cheung M, Juonala M (2015). Development of hypertension in overweight adolescents: A review. Adolesc Health Med Ther. 6: 171–187. doi: 10.2147/AHMT.S55837.

Lim H, Xue H, Wang Y (2014). Association between obesity and metabolic comorbidities among children and adolescents in South Korea based on national data. BMC Pub Health. 14(279). doi: 10.1186/1471-2458-14-279.

Liu K, Li C, Gong H, Guo Y, Hou B, Chen L, Liu F, et al. (2021). Prevalence and risk factors for hypertension in adolescents aged 12 to 17 years: A School-based study in China. Hypertension. 78: 1577 –1585. doi: 10.1161/HYPERTENSION-AHA.121.17300.

Manios Y, Karatzi K, Protogerou AD, Moschonis G, Tsirimiagou C, Androutsos O, Lionis C, et al. (2017). Prevalence of childhood hypertension and hypertension pheno-types by weight status and waist circumference: The Healthy Growth Study. Eur J Nutr. 57(3), 1147–1155. doi: 10.1007/s00394-017-1398-y.

Mohan B, Verma A, Singh K, Singh K, Sharma S, Bansal R, Tandon R, et al. (2019). Prevalence of sustained hypertension and obesity among urban and rural adolescents: A school-based, cross-sectional study in North India. BMJ Open. 9(e027134): 1–9. doi: 10.1136/bmjopen-2018-027134.

Oparil S, Acelajado MC, Bakris GL, Berlowitz DR, Cífková R, Dominiczak AF, Grassi G, et al. (2019). Hypertension. Nat Rev Dis Primers. 4: 1–48. doi: 10.1038/nrdp.2018.14.

Samuels J, Samuel J (2018). New guidelines for hypertension in children and adolescents. J Clin Hyper-tens. 20: 837–839. doi: 10.1111/jch.13285.

Shaumi NRF, Achmad EK (2019). Literature review: Hypertension risk factors among adolescents in Indonesia. Media Litbangkes. 29(2): 115–122. doi: 10.22435/mpk.v29i2.1106.

Singh S, Shankar R, Singh GP (2017). Prevalence and associated risk factors of hypertension: A cross-sectional study in urban Varanasi. Int J Hypertens. doi: 10.1155/2017/5491838.

Soua S, Ghammam R, Maatoug J, Zammit N, Fredj SB, Martinez F, Ghannem H (2022). The prevalence of high blood pressure and its determinants among Tunisian adolescents. J Hum Hypertens. doi: 10.1038/s41371-022-00677-x.

Szabo L, Kormos-Tasi J, Gacsi E, Scheuring N (2021). High blood pressure and obesity prevalence in adolescents: Results of a screening program. Arch Dis Child. 106(2). doi: 10.1136/archdischild-2021-europaediatrics.49.

Wariri O, Jalo I, Bode-Thomas F (2018). Discriminative ability of adiposity measures for elevated blood pressure among adolescents in a resource constrained setting in north-east Nigeria: A cross-sectional analysis. BMC Obes. 5(1): 1–10. doi: 10.1186/s40608-018-0211-7.

WHO (2021a). Hypertension. World Health Organization. Retrieved October 24, 2022, from https://-www.who.int/news-room/factsheets/detail/hypertensi-on.

WHO (2021b). Obesity and overweight. World Health Organization. Retrieved September 10, 2022, from https://www.who.int/news-room/-fact-sheets-/detail/obesity-and-over-weight.

Yang Y, Min J, Chang L, Chai J, Song Z, Zha S, Zhang M, et al. (2021). Prevalence trends of hypertension among 9–17 aged children and adolescents in Yunnan, 2017–2019: a serial cross-sectional surveillance survey. BMC Pub Health. 21(338): 1–9. doi: 10.1186/s1-2889-021-10258-1.

Yusrizal M, Indarto D, Akhyar M (2016). Risk of hypertension in overweight adolescents in Pangkalpinang, Indonesia. J Epidemiol Public Health. 1(1): 27–36. doi: 10.26911/jepublichealth.2016.01.01.04.

Zou Y, Xia N, Zou Y, Chen Z, Wen Y (2019). Smartphone addiction may be associated with adolescent hypertension: A cross-sectional study among junior school students in China. BMC Pediatr. 19(1): 1–8. doi: 10.1186/s12887-019-1699-9.

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Published

2023-02-16

How to Cite

Zaen, N. A., Tamtomo, D., & Ichsan, B. (2023). Effects of Overweight and Obesity on Hypertension in Adolescents: A Meta-Analysis. Journal of Epidemiology and Public Health, 8(1), 109–120. https://doi.org/10.26911/jepublichealth.2023.08.01.10

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