The Benefits of Acupuncture Combined with a Low Purine Diet to Improve Uric Acid and Total Cholesterol in Diabetes Mellitus Patients with Hyperuricemia

Sumanto Sumanto, Joko Tri Haryanto, Heni Nur Kusumawati

Abstract

Backround: Diabetes mellitus with hyperuricemia causes the accumulation of monosodium urate crystals in the synovial joint tissue. The incidence of gout in Indonesia according to the Indonesian Rheumatology Association, namely: gout 1-2 percent of adults, is the most cases of arthritis in men and is estimated to be between 13.6 per 1,000 men and 6.4 per 1,000 women. The prevalence of gout increased with age, an average of 7 percent of men >75 years and 3 percent of women >85 years.

Subjects dan Method: Quasi Experimental with pre and post test designs. The research time is between March to September 2021 at the Posyandu for the elderly in Surakarta City. The population of this study were all objects with fasting blood sugar levels between 100 mg/dl - 125 mg/dl and above 126 mg/dl, female blood uric acid levels exceeding 5.6 mg/dl in men and exceeding 6.5 in the city. Surakarta, sample selection using purposive sampling, sample size 40 subjects. The dependent variable is uric acid, cholesterol and total blood levels, the independent variable is combination acupuncture therapy with a low purine diet. The research instrument used a checklist for blood analysis and physical examination. Data analysis using t test.

Results: Uric acid levels after acupuncture therapy in the intervention group were lower (Mean= 3.31; SD= 0.61) than the control group (Mean= 5.83; SD= 1.29), and not statistically significant (p= 0.935). Total cholesterol level after acupuncture therapy in the intervention group was lower (Mean= 166.00; SD= 34.20) than the control group (Mean= 222.30; SD= 55.43), but it was statistically non-significant (p= 0.676).

Conclusion: Acupuncture therapy can reduce uric acid levels and total cholesterol levels.

Keywords: Acupuncture, low purine diet, uric acid level, cholesterol level

Correspondence: Sumanto. College Leading Basic Research, Acupuncture Course, Health Polyetchnics, Ministry of Health Surakarta. Jl. Letjend Sutoyo Mojosongo, Surakarta, Central Java. Email: sumantoiman­@gmail.com. Mobile phone: 08121608067.

Journal of Epidemiology and Public Health (2022), 07(03): 288-295
https://doi.org/10.26911/jepublichealth.2022.07.03.01.

Full Text:

PDF

References

Ahimsa T, Karema K (2003). Gambaran artritis gout dan beberapa faktor yang mempengaruhi kadar asam urat di Minahasa (overview of gouty arthritis and several factors affecting uric acid levels in Minahasa). Tesis.


Bingyun L, Xinyi W, Jiantong W, Shan W, Xufeng L, Hongyi C, Minghe S (2017). Effect of acupuncture on serum uric acid in rats with hyperuricemia.


Cheng C, Siu A, Rea J, Minesaki Y, Prodoehl C (2011). Traditional Chinese medicine medicated diet recipe book by TCM Diet Group.


Hisatome I, Li P, Taufiq F, Maharani N, Kuwabara M, Ninomiya H, Udin Bahrudin (2020). Hyperuricemia as a risk factor for cardiovascular diseases. Hyperuricemia as a risk factor for cardiovascular diseases. J Biomed Transl Res. 6(3): 101-109. doi: 10.14710/jbtr.v6i3.9383.


Ishak A (2014). Hubungan antara kadar asam urat dengan kadar gula darah pada penderita diabetes mellitus tipe 2. Thesis. 1 Departemen Patologi Klinik Fakultas Kedokteran Universitas Sumatera Utara / RSUP H Adam Malik Medan (1), Burhanuddin Nasution (1), Dharma Lindarto (2) 2 Departemen Ilmu Penyakit Dalam Divisi Endokrinologi Fakultas Kedokteran Universitas Sumatera Utara/ RSUP H Adam Malik Medan (The relationship between uric acid levels with blood sugar levels in patients with type 2 diabetes mellitus. Thesis. 1 Department of Clinical Pathology, Faculty of Medicine, University of North Sumatra / RSUP H Adam Malik Medan (1), Burhanuddin Nasution (1), Dharma Lindarto (2) 2 Department of Internal Medicine Division of Endocrinology, Faculty of Medicine, University of North Sumatra/ RSUP H Adam Malik Medan).


Jun P, Boling H, Yushun L, Yuyan Z, Zhiyong H, Richardson F (2000). Treatment of gout with acupuncture. Acupunct Med. 18(1): 29-31. doi: 10.1136/aim.18.1.29.


Kerner W, Brückel J (2014). Definition, classification and diagnosis of diabetes mellitus. Exp Clin Endocrinol Diabetes. 122(7): 384-386. doi: 10.1055/s00341366278.


Kris T, Ivan K, Ika R (2020). Metabolisme purin & pirimidin gangguan & dampaknya bagi kesehatan (Purine & pyrimidine metabolism disorders & their impact on health). Format: Book application/pdf. Bahasa: ind. Terbitan: Penerbit Andi. Online Access: http://repository.ukrida.ac.id//handle/123456789/267.


Kushiyama A, Tanaka K, Hara S, Kawazu S (2014). Linking uric acid metabolism to diabetic complications. World J Diabetes. 5(6): 787-795. doi: 10.4239/wjd.v5.i6.787.


Lee WB, Woo SH, Min BI, Cho SH (2013). Acupuncture for gouty arthritis: a concise report of a systematic and meta-analysis approach. Rheumatology. 52(7): 1225-1232. doi: 10.1093/rheumatology/ket013.


Maiuolo J, Oppedisano F, Gratteri S, Muscoli C, Mollace V (2015) Regulation of uric acid metabolism and excretion. Int J Cardiol. (213):8-14. doi: 10.1016/j.ijcard.2015.08.109.


Peng Q, Yao X, Xiang J, Wang Y, Lin X (2018). Acupuncture for hyperlipidemia. Medicine, 97(50): e13041. doi: 10.1097/md.0000000000013041.


Putra HTR (2007). Artikel: Hubungan konsumsi purin dengan hiperurisemia pada suku bali di daerah pariwisata pedesaan. (The Relationship between Purine Consumption and Hyperuricemia in Balinese in Rural Tourism Areas. Journal of Internal Medicine. Jilid. 8. Terbitan1. Halaman 37-43.


Sastiani (2004). Hipertensi (Hypertension). Jakarta: Gramedia Pustaka utama.


Smelter, Bare (2002). Textbook Medical Surgical Nursing. Diterjemahkan bahasa Indonesia: Buku Ajar Keperawatan Medika Bedah. Jakarta: EGC.


Zhang X, ValLaillet D (2021). Review article obesity animal models for acupuncture and related therapy research studies. Evid.based Complement. Altern. 1-29. doi: 10.1155/2021/6663397.

Refbacks

  • There are currently no refbacks.