The Effect of Obesity, Oral Contraceptive and Passive Smoking on the Risk of Cervical Cancer

Authors

  • Roiela Arfailasufandi Masters Program in Public Health, Universitas Sebelas Maret
  • Ambar Mudigdo Masters Program in Public Health, Universitas Sebelas Maret
  • Aris Sudiyanto Faculty of Medicine, Universitas Sebelas Maret

Abstract

Background: Studies have investigated the effects of obesity on cancer development. However, the relationship between obesity and cervical cancer risk is unclear. This study aimed to determine the effect of obesity, oral contraceptive and passive smoking on the risk of cervical cancer.

Subjects and Method: A case-control study was conducted at Dr. Moewardi Hospital, from October to December 2018. A sample of 200 patients was selected by fixed disease sampling, consisting of 100 cervical cancer patients and 100 noncervical cancer patients. The dependent variable was cervical cancer. The independent variables were obesity, oral contraceptive use, smoking exposure, parity, age at first sexual intercourse, and family history. The data were obtained from the medical record. The data were analyzed by multiple logistic regression.

Results:The risk of cervical cancer increased with obesity (OR= 6.83; 95%CI= 2.44 to 19.17; p<0.001), cigarette smoke exposure (OR= 12.57; 95% CI= 4.59 to 34.41; p<0.001),oral contra

References

American Cancer Society (2017). Cervical cancer causes, risk factors, and prevention. American Cancer Society.

Ardahan M (2016). Incidence, risk factors, diagnostic criteria and prevention methods in cervical cancer. Recent Advances in Cervical Cancer.

Assoumou SZ, Mabika BM, Mbiguino M, Mouallif A, Khattabi, Ennaji MM (2015). Awareness and knowledge regarding cervical cancer, Pap smear screening, and human papillomavirus infection in Gabonese women. BMC Women

Baussano I, Diaz M, Tully S, Munoz N, San-jose S, Bosch FX, Franceschi S (2017). Effect of an age difference between heterosexual partners on the risk of cervical cancer and human papillomavirus infection. Papilloma-virus Research 3 98-104.

Chelimo C, Wouldes TA, Cameron LD, El-wood JM (2013). Risk factors for and prevention of human papilloma-viruses (HPV), genital warts and cervical cancer. Journal of Infection 66: 207-217. https://www.sciencedirect.com/science/article/pii/S01634453-12003106

Dewi W (2017). Sebaran Kanker di Indonesia, Riset Kesehatan Dasar 2007. Indonesian Journal of Cancer 11(1).

El-Moselhy EA, Borg HM, Atlam SA (2016). Cervical cancer: Sociodemographic and clinical risk factors among adult Egyptian Females. Advances Oncology Research and Treatments 1:1.

Irime S, Vladd M, Mirestean IM O, Balacescu M, Rus (2011). Risk Factors in a Sample of Patients with Advanced Cervical Cancer. Apll Med Informatics 29:1-10.

Kementerian Kesehatan Republik Indonesia (2015). Panduan Nasional Penanganan Kanker, Kanker Serviks. Komite Nasional Penanggulangan Kanker (KPKN). Kementerian Kesehatan Republik Indonesia. Jakarta.

_____ (2015). Pusat Data dan Informasi. Kementerian Kesehatan Republik Indonesia. Jakarta.

_____ (2017). Data dan Informasi: Profil Kesehatan Indonesia 2016. Kementerian Kesehatan Republik Indonesia. Jakarta.

Lee JK, So KA, Piyathilake CJ, Kim MK (2013). Mild obesity, physical activity, calorie intake, and the risks of cervical intraepithelial neoplasia and cervical cancer. PloS One, 8(6): e66555.

Momenimovahed Z, Salehiniya H (2017). Incidence, mortality and risk factors of cervical cancer in the world. Biomedical Research & Therapy.

Natphopsuk S, Settheetham Ishida W, Sinawat S, Pientong C, Yuenyao P, Ishida T (2012). Risk factors for cervical cancer in Northeastern Thailand: Detailed analyses of sexual and smoking behavior. Asian Pacific Journal of Cancer Prevention 13(11): 5489-5495. http://journal.waocp.org/?sid=Entrez:PubMed&id=pmid:23317205&key=2012.13.11.5489

Poorolajal J, Jenabi E (2016). The association between BMI and cervical cancer risk: A meta-analysis. European Journal of Cancer Prevention. 25(3): 232-238.

Raychaudhuri S, Mandal S (2012). Socio-demographic and behavioral risk factors for cervical cancer and knowledge. attitude and practice in rural and urban areas of North Bengal, India. Asian Pacific Journal of Cancer Prevention 13(4): 1093. http://journal.waocp.org/article_26298_e73d0143926839642144a3724161d93.pdf

Ruiz AM, Ruiz JE, Gavilanes AV, Eriksson T, Lehtinen M, Perez G, Sings HL, James MK, Haupt RM (2012). The proximity of first sexual intercourse to menarche and risk of high- grade cervical disease. The Journal of Infectious Disease 206: 1887-96. https://-academic.oup.com/jid/article/206/-12/1887/864598

Savitri A (2015). Kupas tuntas kanker payudara, leher rahim & rahim. Penerbit Pustaka Baru Press. Yogyakarta.

Sharma P, Pattanshetty SM (2018). A study on risk factors of cervical cancer among patients attending a tertiary care hospital: A case-control study. Clinical Epidemiology and Global Health 6: 83-87.

Seng LM, Rosman AN, Khan A, Haris NM, Mustapha NAS, Husaini NSM, Zahari NF (2018). Awareness of cervical cancer among women in Malaysia. International Journal of Health Sciences 12(4): 1658-3639. https://www.ncbi.-nlm.nih.gov/pmc/articles/PMC6040851/pdf/IJHS-12-42.pdf

World Health Organization (2014). Comprehensive cervical cancer control a guide to essential practice second edition. World Health Organization.

Yayasan Kanker Indonesia (2017). Harapan terpadu: Melantun kebersamaan be-rantas kanker. Yayasan Kanker Indo-nesia. Jakarta.

Yoruk S, Acikgoz A, Ergor G (2016). Determination of knowledge levels, attitude, and behaviors of female university students concerning cervical cancer, human papillomavirus, and its vaccine. BMC Women's Health. 16: 51. https://dx.doi.org/10.1186%2Fs12905-016-0330-6.

Zeng X, Ping-An X, Fen W, Chun-Yi L, Juan Y, Yi G (2012). Passive smoking and cervical cancer risk: A meta-analysis based on 3,230 cases and 2,982 controls. Asian Pacific Journal of Cancer Prevention 13(6): 2687. http://journal.-waocp.org/article_26559_459d-2c10cc128e6264c53b1866ba1436.pdf

Downloads

How to Cite

Arfailasufandi, R., Mudigdo, A., & Sudiyanto, A. (2019). The Effect of Obesity, Oral Contraceptive and Passive Smoking on the Risk of Cervical Cancer. Journal of Epidemiology and Public Health, 4(3), 189–197. Retrieved from https://jepublichealth.com/index.php/jepublichealth/article/view/141

Issue

Section

Articles

Most read articles by the same author(s)

1 2 > >>